Water → 7-Amino-8-bromo-2,4,4-trimethyl-1,2,3,4-tetrahydroisoquinoline
Reaction equation
[Br:15][N:16]1[C:17](=[O:18])[CH2:19][CH2:20][C:21]1=[O:22].[CH3:23][C:24]#[N:25].[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[CH2:9][N:8]([CH3:12])[CH2:7][C:6]2([CH3:13])[CH3:14].[OH2:26]>>[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([c:11]1[Br:15])[CH2:9][N:8]([CH3:12])[CH2:7][C:6]2([CH3:13])[CH3:14]Participants
5
Sources & evidence
- ORD record
- ord-219971ac930c47218cdb100089726374
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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