3-Chlorothiophene-2-carbonyl chloride → 3-chloro-N-[3-[4-[3-(2-methylpropanoylamino)phenyl]piperidin-1-yl]-1-phenylpropyl]thiophene-2-carboxamide
Reaction equation
[Cl:1][c:2]1[c:3]([C:7](=[O:8])[Cl:9])[s:4][cH:5][cH:6]1.[NH2:10][CH:11]([CH2:12][CH2:13][N:14]1[CH2:15][CH2:16][CH:17]([c:20]2[cH:21][c:22]([NH:26][C:27]([CH:28]([CH3:29])[CH3:30])=[O:31])[cH:23][cH:24][cH:25]2)[CH2:18][CH2:19]1)[c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[Cl:1][c:2]1[c:3]([C:7](=[O:8])[NH:10][CH:11]([CH2:12][CH2:13][N:14]2[CH2:15][CH2:16][CH:17]([c:20]3[cH:21][c:22]([NH:26][C:27]([CH:28]([CH3:29])[CH3:30])=[O:31])[cH:23][cH:24][cH:25]3)[CH2:18][CH2:19]2)[c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[s:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-539521392042448e89716200fc50f8bf
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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