Benzo(b)thiophene-2-carboxylic acid → N-[4-(1-benzylpiperidin-4-yloxy)-3-cyanophenyl]benzo[b]thiophene-2-carboxamide
Reaction equation
[NH2:13][c:14]1[cH:15][cH:16][c:17]([O:22][CH:23]2[CH2:24][CH2:25][N:26]([CH2:29][c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[CH2:27][CH2:28]2)[c:18]([C:19]#[N:20])[cH:21]1.[s:1]1[c:2]2[c:3]([cH:4][c:5]1[C:6](=[O:7])[OH:8])[cH:9][cH:10][cH:11][cH:12]2>>[s:1]1[c:2]2[c:3]([cH:4][c:5]1[C:6](=[O:8])[NH:13][c:14]1[cH:15][cH:16][c:17]([O:22][CH:23]3[CH2:24][CH2:25][N:26]([CH2:29][c:30]4[cH:31][cH:32][cH:33][cH:34][cH:35]4)[CH2:27][CH2:28]3)[c:18]([C:19]#[N:20])[cH:21]1)[cH:9][cH:10][cH:11][cH:12]2Participants
3
Sources & evidence
- ORD record
- ord-72ba3817092f4592ab8b57b788a7324a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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