Iodopyrazine → 6-Methyl-4-pyrazin-2-yl-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide

HRID 801532Notes

Reaction equation

HRID 801532 reaction equation
[CH3:1][c:2]1[n:3][c:4]([NH:7][C:8](=[O:9])[c:10]2[n:11][c:12]([CH3:25])[cH:13][c:14]([B:16]3[O:17][C:18]([CH3:19])([CH3:20])[C:21]([CH3:22])([CH3:23])[O:24]3)[cH:15]2)[s:5][cH:6]1.[I:26][c:27]1[n:28][cH:29][cH:30][n:31][cH:32]1>>[CH3:1][c:2]1[n:3][c:4]([NH:7][C:8](=[O:9])[c:10]2[n:11][c:12]([CH3:25])[cH:13][c:14](-[c:27]3[n:28][cH:29][cH:30][n:31][cH:32]3)[cH:15]2)[s:5][cH:6]1

Participants

3

Reactant 2

HCID 642841IodopyrazineHCID 497604122-Pyridinecarboxamide, 6-methyl-N-(4-methyl-2-thiazolyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-

Product 1

HCID 248208796-Methyl-4-pyrazin-2-yl-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide

Sources & evidence

ORD record
ord-f714ecc585bd40bf9328bcd8129d0535
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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