Methanol → Methyl 2,5-Dichloronicotinate

HRID 801650Notes

Reaction equation

[CH3:16][OH:17].[CH3:18][CH2:19][O:20][CH2:21][CH3:22].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([Cl:11])[cH:9][n:10]1.[S:12]([Cl:13])([Cl:14])=[O:15]>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH3:16])[cH:7][c:8]([Cl:11])[cH:9][n:10]1

Participants

Reactant 4

HCID 887Methanol

HCID 3283Diethyl Ether

HCID 24386Thionyl Chloride

HCID 27360852,5-Dichloropyridine-3-carboxylic acid

Product 1

HCID 2764318Methyl 2,5-Dichloronicotinate

Sources & evidence

ORD record: ord-6da2dd33c3e94fa4b2cd507cedfa2fb2
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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