1-(Methanesulfonyl)piperidin-4-amine → [2-Amino-6-(1-methanesulfonyl-piperidin-4-ylamino)-pyridin-3-yl]-(4-fluoro-phenyl)-methanone
Reaction equation
[CH3:18][S:19](=[O:20])(=[O:21])[N:22]1[CH2:23][CH2:24][CH:25]([NH2:28])[CH2:26][CH2:27]1.[NH2:1][c:2]1[n:3][c:4]([Cl:17])[cH:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[cH:11][cH:12][c:13]([F:16])[cH:14][cH:15]1>>[NH2:1][c:2]1[n:3][c:4]([NH:28][CH:25]2[CH2:24][CH2:23][N:22]([S:19]([CH3:18])(=[O:20])=[O:21])[CH2:27][CH2:26]2)[cH:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[cH:11][cH:12][c:13]([F:16])[cH:14][cH:15]1Participants
3
Sources & evidence
- ORD record
- ord-9fc5588171794c9da7f4254b80fd0047
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…