Acetone → 1-(3,3-Diphenyl-2-propenyl)-4-ethynyl-4-hydroxypiperidine

HRID 801805Notes

Reaction equation

HRID 801805 reaction equation
[C:17](#[CH:18])[C:19]1([OH:25])[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]1.[C:26](=[O:27])([O-:28])[O-:29].[CH3:32][C:33](=[O:34])[CH3:35].[K+:30].[K+:31].[c:1]1([C:7](=[CH:8][CH2:9][Br:10])[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([C:7](=[CH:8][CH2:9][N:22]2[CH2:21][CH2:20][C:19]([C:17]#[CH:18])([OH:25])[CH2:24][CH2:23]2)[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 123465451,1'-(3-Bromoprop-1-ene-1,1-diyl)dibenzeneHCID 198955804-Ethynylpiperidin-4-ol

Product 1

HCID 198955791-(3,3-Diphenyl-2-propenyl)-4-ethynyl-4-hydroxypiperidine

Sources & evidence

ORD record
ord-d001adf04e0946618fb92cbc478d41b9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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