1-(2-Bromoethyl)-3-fluorobenzene → 1-[1-(3-Fluorophenethyl)piperdin-4-yl]-6-acetamidomethylindoline
Reaction equation
[F:21][c:22]1[cH:23][c:24]([CH2:25][CH2:26][Br:27])[cH:28][cH:29][cH:30]1.[NH:1]1[CH2:2][CH2:3][CH:4]([N:7]2[CH2:8][CH2:9][c:10]3[cH:11][cH:12][c:13]([CH2:16][NH:17][C:18]([CH3:19])=[O:20])[cH:14][c:15]32)[CH2:5][CH2:6]1>>[N:1]1([CH2:26][CH2:25][c:24]2[cH:23][c:22]([F:21])[cH:30][cH:29][cH:28]2)[CH2:2][CH2:3][CH:4]([N:7]2[CH2:8][CH2:9][c:10]3[cH:11][cH:12][c:13]([CH2:16][NH:17][C:18]([CH3:19])=[O:20])[cH:14][c:15]32)[CH2:5][CH2:6]1Participants
3
Sources & evidence
- ORD record
- ord-1a9262a2d9604ba3b777cd0f6a2a99c6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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