Ethyl 4-bromo-5-(3-chloro-4-fluorophenyl)furan-2-carboxylate → Ethyl 5-(3-chloro-4-fluorophenyl)-4-(3-chloro-5-fluorophenyl)furan-2-carboxylate
Reaction equation
[Br:27][c:28]1[cH:29][c:30]([C:41](=[O:42])[O:43][CH2:44][CH3:45])[o:31][c:32]1-[c:33]1[cH:34][c:35]([Cl:40])[c:36]([F:39])[cH:37][cH:38]1.[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[cH:10][c:11]([C:12]([O:13][CH2:14][CH3:15])=[O:16])[o:17][c:18]2-[c:19]2[cH:20][cH:21][cH:22][c:23]([C:24]#[N:25])[cH:26]2)[cH:5][c:6]([F:8])[cH:7]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:28]2[cH:29][c:30]([C:41](=[O:42])[O:43][CH2:44][CH3:45])[o:31][c:32]2-[c:33]2[cH:34][c:35]([Cl:40])[c:36]([F:39])[cH:37][cH:38]2)[cH:5][c:6]([F:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-0207d4f89e2241f59e7f0e9fffc64280
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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