Potassium Cation → 1-Benzyl-2-methyl-4-(3-(N-[isobutyl]-N-[cyano]amino)-4-nitrophenyl)-5-(2,4-difluorophenyl)-1H-imidazole

HRID 802208Notes

Reaction equation

HRID 802208 reaction equation
[C:23](#[N:24])[N:25]([c:26]1[c:27]([N+:40](=[O:41])[O-:42])[cH:28][cH:29][c:30]([B:32]2[O:33][CH2:34][C:35]([CH3:36])([CH3:37])[CH2:38][O:39]2)[cH:31]1)[CH2:43][CH:44]([CH3:45])[CH3:46].[C:47](=[O:48])([O-:49])[O-:50].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([CH3:22])[n:10][c:11]([Br:21])[c:12]1-[c:13]1[c:14]([F:20])[cH:15][c:16]([F:19])[cH:17][cH:18]1.[K+:51].[K+:52].[O:53]1[CH2:54][CH2:55][O:56][CH2:57][CH2:58]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([CH3:22])[n:10][c:11](-[c:30]2[cH:29][cH:28][c:27]([N+:40](=[O:41])[O-:42])[c:26]([N:25]([C:23]#[N:24])[CH2:43][CH:44]([CH3:45])[CH3:46])[cH:31]2)[c:12]1-[c:13]1[c:14]([F:20])[cH:15][c:16]([F:19])[cH:17][cH:18]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 179816721-benzyl-2-methyl bromo-5-(2,4-difluorophenyl)-1H-imidazoleHCID 86623267N-[cyano]N-[isobutyl]2-nitro-5-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)aniline

Product 1

HCID 866232661-Benzyl-2-methyl-4-(3-(N-[isobutyl]-N-[cyano]amino)-4-nitrophenyl)-5-(2,4-difluorophenyl)-1H-imidazole

Sources & evidence

ORD record
ord-589c26cca7c54db28bf224dbe354e7b4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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