Toluene → tert-Butyl 4-(5-(hydroxymethyl)-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperazine-1-carboxylate

HRID 802816Notes

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]3[n:16]([c:17]([C:20](=[O:21])[O:22][CH3:23])[cH:18][n:19]2)[cH:24][n:25][n:26]3)[CH2:12][CH2:13]1.[CH2:28]([Al+:29][CH2:30][CH:31]([CH3:32])[CH3:33])[CH:34]([CH3:35])[CH3:36].[CH3:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[Cl:44][CH2:45][Cl:46].[H-:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]3[n:16]([c:17]([CH2:20][OH:21])[cH:18][n:19]2)[cH:24][n:25][n:26]3)[CH2:12][CH2:13]1