2-chloro-6-methyl-5H,6H,7H-pyrrolo(3,4-b)pyridin-7-one → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-[(6-methyl-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)amino]thiophene-3-carboxamide
Reaction equation
[Cl:22][c:23]1[cH:24][cH:25][c:26]2[c:27]([n:28]1)[C:29](=[O:33])[N:30]([CH3:32])[CH2:31]2.[NH2:1][c:2]1[s:3][c:4](-[c:10]2[c:11]([F:21])[cH:12][c:13]([C:17]([CH3:18])([CH3:19])[OH:20])[cH:14][c:15]2[F:16])[cH:5][c:6]1[C:7](=[O:8])[NH2:9]>>[NH:1]([c:2]1[s:3][c:4](-[c:10]2[c:11]([F:21])[cH:12][c:13]([C:17]([CH3:18])([CH3:19])[OH:20])[cH:14][c:15]2[F:16])[cH:5][c:6]1[C:7](=[O:8])[NH2:9])[c:23]1[cH:24][cH:25][c:26]2[c:27]([n:28]1)[C:29](=[O:33])[N:30]([CH3:32])[CH2:31]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-486a5c4cacd74d008a202f2890220be6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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