Sodium ion → 4-(2-chloro-4-methoxy-phenyl)-N2-(1-cyclobutyl-propyl)-pyridine-2,3-diamine

HRID 803042Notes

Reaction equation

HRID 803042 reaction equation
[Cl:1][c:2]1[c:3](-[c:10]2[c:11]([N+:24]([O-:25])=[O:26])[c:12]([NH:16][CH:17]([CH2:18][CH3:19])[CH:20]3[CH2:21][CH2:22][CH2:23]3)[n:13][cH:14][cH:15]2)[cH:4][cH:5][c:6]([O:8][CH3:9])[cH:7]1.[Na+:33].[Na+:34].[S:27]([S:28]([O-:29])=[O:30])([O-:31])=[O:32]>>[Cl:1][c:2]1[c:3](-[c:10]2[c:11]([NH2:24])[c:12]([NH:16][CH:17]([CH2:18][CH3:19])[CH:20]3[CH2:21][CH2:22][CH2:23]3)[n:13][cH:14][cH:15]2)[cH:4][cH:5][c:6]([O:8][CH3:9])[cH:7]1

Participants

4

Reactant 3

HCID 923Sodium ion2×HCID 1086DithioniteHCID 22052220[4-(2-Chloro-4-methoxy-phenyl)-3-nitro-pyridin-2-yl]-(1-cyclobutyl-propyl)-amine

Product 1

HCID 696581654-(2-chloro-4-methoxy-phenyl)-N2-(1-cyclobutyl-propyl)-pyridine-2,3-diamine

Sources & evidence

ORD record
ord-abdd162ade8c466cba77573018dc9139
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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