1-(3,5-Difluorophenyl)piperazine → 1-[(2-Methylquinolin-3-yl)aminothiocarbonyl]-4-(3,5-difluorophenyl)piperazine
Reaction equation
[CH3:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[cH:10][c:11]1[NH:12][C:13]([O:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)=[S:21].[F:22][c:23]1[cH:24][c:25]([N:30]2[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]2)[cH:26][c:27]([F:29])[cH:28]1>>[CH3:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[cH:10][c:11]1[NH:12][C:13](=[S:21])[N:33]1[CH2:32][CH2:31][N:30]([c:25]2[cH:24][c:23]([F:22])[cH:28][c:27]([F:29])[cH:26]2)[CH2:35][CH2:34]1Participants
3
Sources & evidence
- ORD record
- ord-aec887c33fbd415080298fbf97477ec1
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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