Cyclopentylacetyl chloride → 2-cyclopentyl-N-[(3RS,4SR)-1-(1-cyclopropylmethyl-piperidine-4-carbonyl)-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-N-methyl-acetamide

HRID 803248Notes

Reaction equation

HRID 803248 reaction equation
[CH:1]1([CH2:4][N:5]2[CH2:6][CH2:7][CH:8]([C:11](=[O:12])[N:13]3[CH2:14][CH:15]([c:20]4[cH:21][c:22]([Cl:27])[c:23]([Cl:26])[cH:24][cH:25]4)[CH:16]([NH:18][CH3:19])[CH2:17]3)[CH2:9][CH2:10]2)[CH2:2][CH2:3]1.[CH:28]1([CH2:33][C:34](=[O:35])[Cl:36])[CH2:29][CH2:30][CH2:31][CH2:32]1>>[CH:1]1([CH2:4][N:5]2[CH2:6][CH2:7][CH:8]([C:11](=[O:12])[N:13]3[CH2:14][CH:15]([c:20]4[cH:21][c:22]([Cl:27])[c:23]([Cl:26])[cH:24][cH:25]4)[CH:16]([N:18]([CH3:19])[C:34]([CH2:33][CH:28]4[CH2:29][CH2:30][CH2:31][CH2:32]4)=[O:35])[CH2:17]3)[CH2:9][CH2:10]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 3485182Cyclopentylacetyl chlorideHCID 67025771(1-cyclopropylmethyl-piperidin-4-yl)-[(3SR,4RS)-3-(3,4-dichloro-phenyl)-4-methylamino-pyrrolidin-1-yl]-methanone

Product 1

HCID 670256222-cyclopentyl-N-[(3RS,4SR)-1-(1-cyclopropylmethyl-piperidine-4-carbonyl)-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-N-methyl-acetamide

Sources & evidence

ORD record
ord-36024e884860420597210dd48350cf9c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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