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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 803271Generated: October 26, 2026

Chloride → 5-{[4,4-Dimethyl-6-fluoro-2-hydroxy-5-methoxy-2-trifluoromethyl-1,2,3,4-tetrahydronaphthalen-1-yl]amino}-quinolin-2(1H)-one

https://huagongshe.com/reaction/803271

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantTitanium cation (4+)HCID 114942—
Reactant5-Amino-1,2-dihydroquinolin-2-oneHCID 15719078—
Reactant4-(3-Fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentanalHCID 17989086—
Product5-{[4,4-Dimethyl-6-fluoro-2-hydroxy-5-methoxy-2-trifluoromethyl-1,2,3,4-tetrahydronaphthalen-1-yl]amino}-quinolin-2(1H)-oneHCID 68680484—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-25e67b23ddcc4525bbef3337740a40c1
Source noteTest data from https://doi.org/10.1039/C8SC04228D