1-(aminomethyl)-N,N-dimethylcyclobutan-1-amine → 4-{[4-Amino-5-(2,6-difluorobenzoyl)-1,3-thiazol-2-yl]amino}-N-{[1-(dimethylamino)cyclobutyl]methyl}benzamide
Reaction equation
[NH2:1][c:2]1[n:3][c:4]([NH:17][c:18]2[cH:19][cH:20][c:21]([C:22](=[O:23])[OH:24])[cH:25][cH:26]2)[s:5][c:6]1[C:7]([c:8]1[c:9]([F:15])[cH:10][cH:11][cH:12][c:13]1[F:14])=[O:16].[NH2:27][CH2:28][C:29]1([N:33]([CH3:34])[CH3:35])[CH2:30][CH2:31][CH2:32]1>>[NH2:1][c:2]1[n:3][c:4]([NH:17][c:18]2[cH:19][cH:20][c:21]([C:22](=[O:24])[NH:27][CH2:28][C:29]3([N:33]([CH3:34])[CH3:35])[CH2:30][CH2:31][CH2:32]3)[cH:25][cH:26]2)[s:5][c:6]1[C:7]([c:8]1[c:9]([F:15])[cH:10][cH:11][cH:12][c:13]1[F:14])=[O:16]Participants
3
Sources & evidence
- ORD record
- ord-33bbdf4f232546b0b4ded59e88f183e8
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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