HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenethylamine, (-)- → (S)-3-(1-phenylethylamino)methylenedihydrofuran-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenethylamine, (-)- | HCID 75818 | — |
| Reactant | HCID 66988753 | HCID 66988753 | — |
| Product | (S)-3-(1-phenylethylamino)methylenedihydrofuran-2-one | HCID 66988142 | 73% |
Reaction Steps
Using 3-hydroxymethylenedihydrofuran-2-one sodium salt (50 mmol) and (S)-1-phenylethylamine (55 mmol) and proceeding according to the abovementioned method A1, (S)-3-(1-phenylethylamino)methylenedihydrofuran-2-one (7.92 g, efficiency: 73%) is produced in the form of a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846125B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-5b6a8e4101d749b691a34c0057d8db65 |
| Source note | uspto-grants-2014_09 |