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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 803319Generated: October 25, 2026

Chloroform → 3-cyclopropyl-alpha-hydroxy-2,5-dihydro-5-oxo-1-phenyl-alpha-trifluoromethyl-1H-pyrazole-4-acetic acid methyl ester

https://huagongshe.com/reaction/803319

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroformHCID 6212—
ReactantMethyl 3,3,3-trifluoro-2-oxopropanoateHCID 2734931—
Reactant5-cyclopropyl-2-phenyl-1H-pyrazol-3-oneHCID 66022699—
Product3-cyclopropyl-alpha-hydroxy-2,5-dihydro-5-oxo-1-phenyl-alpha-trifluoromethyl-1H-pyrazole-4-acetic acid methyl esterHCID 66701601—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-e514bba9cd4148fd869c00ed86885139
Source noteTest data from https://doi.org/10.1039/C8SC04228D