HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one → 4-carboxy-2-(4-chlorocinnamyl)-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one | HCID 21991416 | — |
| Reactant | 2-(4-chlorocinnamyl)-6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one | HCID 54156036 | — |
| Product | 4-carboxy-2-(4-chlorocinnamyl)-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one | HCID 53794618 | 98.2% |
Reaction Steps
Following the procedure of Example 1 (7), 2-(4-chlorocinnamyl)-6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one was reacted to yield the title compound as a pale yellow crystalline powder (yield: 98.2%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087606B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-c3de29e6ed0e4d46a8fd09b899695f45 |
| Source note | uspto-grants-2006_08 |