Potassium Cation → cis-[4-(4-Benzyloxy-phenyl)-cyclohexyl]-(3-p-tolyl-propyl)-amine

HRID 803515Notes

Reaction equation

HRID 803515 reaction equation
[Br:28][CH2:29][CH2:30][CH2:31][c:32]1[cH:33][cH:34][c:35]([CH3:38])[cH:36][cH:37]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([CH:15]2[CH2:16][CH2:17][CH:18]([NH2:21])[CH2:19][CH2:20]2)[cH:13][cH:14]1.[CH3:39][C:40](=[O:41])[CH2:42][CH3:43].[K+:22].[K+:23].[O-:24][C:25]([O-:26])=[O:27].[OH2:44]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([CH:15]2[CH2:16][CH2:17][CH:18]([NH:21][CH2:29][CH2:30][CH2:31][c:32]3[cH:33][cH:34][c:35]([CH3:38])[cH:36][cH:37]3)[CH2:19][CH2:20]2)[cH:13][cH:14]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6569Methyl Ethyl KetoneHCID 19660Carbonate IonHCID 140848591-(3-Bromopropyl)-4-methylbenzeneHCID 21260521trans 4-(4-Benzyloxy-phenyl)-cyclohexyl-amine

Product 1

HCID 21260485cis-[4-(4-Benzyloxy-phenyl)-cyclohexyl]-(3-p-tolyl-propyl)-amine

Sources & evidence

ORD record
ord-fc943546a8574694a8b26c348b083d0f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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