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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 803517Generated: October 25, 2026

Water → 4-Chloro-7-{5-[4-(2-hydroxyethyl)piperazin-1-ylcarbonyl]-1-methylindol-2-yl}isoindolinone

https://huagongshe.com/reaction/803517

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
Reactant1-(2-Hydroxyethyl)piperazineHCID 7677—
ReactantEthyl AcetateHCID 8857—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant4-Chloro-7-(5-carboxy-1-methylindol-2-yl)isoindolinoneHCID 68492178—
Product4-Chloro-7-{5-[4-(2-hydroxyethyl)piperazin-1-ylcarbonyl]-1-methylindol-2-yl}isoindolinoneHCID 68487483—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-4b227d20cadc4df8b1296a332dd81805
Source noteTest data from https://doi.org/10.1039/C8SC04228D