Cyclohexanecarbonyl chloride → N-[6-(4-Chlorobenzyl)-1-(2,4-dichlorobenzenesulfonyl)-8-isopropyl-4,7-dioxooctahydropyrazino[1,2-a]pyrimidin-3-yl]cyclohexanecarboxamide

HRID 803585Notes

Reaction equation

[CH:1]1([C:7](=[O:8])[Cl:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[NH2:10][CH:11]1[CH2:12][N:13]([S:34](=[O:35])(=[O:36])[c:37]2[c:38]([Cl:44])[cH:39][c:40]([Cl:43])[cH:41][cH:42]2)[CH:14]2[N:15]([C:16]1=[O:17])[CH:18]([CH2:26][c:27]1[cH:28][cH:29][c:30]([Cl:33])[cH:31][cH:32]1)[C:19](=[O:25])[N:20]([CH:22]([CH3:23])[CH3:24])[CH2:21]2>>[CH:1]1([C:7](=[O:8])[NH:10][CH:11]2[CH2:12][N:13]([S:34](=[O:35])(=[O:36])[c:37]3[c:38]([Cl:44])[cH:39][c:40]([Cl:43])[cH:41][cH:42]3)[CH:14]3[N:15]([C:16]2=[O:17])[CH:18]([CH2:26][c:27]2[cH:28][cH:29][c:30]([Cl:33])[cH:31][cH:32]2)[C:19](=[O:25])[N:20]([CH:22]([CH3:23])[CH3:24])[CH2:21]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

Reactant 2

HCID 75938Cyclohexanecarbonyl chloride

HCID 591342523-Amino-6-(4-chlorobenzyl)-1-(2,4-dichlorobenzenesulfonyl)-8-isopropylhexahydropyrazino[1,2-a]pyrimidine-4,7-dione

Product 1

HCID 59134002N-[6-(4-Chlorobenzyl)-1-(2,4-dichlorobenzenesulfonyl)-8-isopropyl-4,7-dioxooctahydropyrazino[1,2-a]pyrimidin-3-yl]cyclohexanecarboxamide

Sources & evidence

ORD record: ord-24bf8c14c1054a598c0823cd1613e344
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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