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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 803669Generated: October 25, 2026

Acetonitrile → 1-(2-fluoro-5-methylphenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-propyne

https://huagongshe.com/reaction/803669

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantCarbonate IonHCID 19660—
Reactant3-Bromo-4-fluorotolueneHCID 96745—
ReactantTetrahydro-2-(2-propynyloxy)-2H-pyranHCID 98609—
ReactantCesium cationHCID 104967—
Reactant2-Dicyclohexylphosphino-2',4',6'-triisoprophylbiphenylHCID 11155794—
Product1-(2-fluoro-5-methylphenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-propyneHCID 59407681—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-823d582a300949f9bd3301835f014bf1
Source noteTest data from https://doi.org/10.1039/C8SC04228D