Pipecolic Acid → 1-(1H-benzo[d]imidazol-2-ylsulfonyl)-2-piperidinecarboxylic acid

HRID 804028Notes

Reaction equation

HRID 804028 reaction equation
[C:1]([CH:2]([CH:3]([C:4]([OH:5])=[O:6])[OH:7])[OH:8])([OH:9])=[O:10].[NH:11]1[CH:12]([C:17](=[O:18])[OH:19])[CH2:13][CH2:14][CH2:15][CH2:16]1.[Na+:34].[OH-:33].[nH:20]1[c:21]([S:29](=[O:30])(=[O:31])[Cl:32])[n:22][c:23]2[c:24]1[cH:25][cH:26][cH:27][cH:28]2>>[N:11]1([S:29]([c:21]2[nH:20][c:24]3[c:23]([n:22]2)[cH:28][cH:27][cH:26][cH:25]3)(=[O:30])=[O:31])[CH:12]([C:17](=[O:18])[OH:19])[CH2:13][CH2:14][CH2:15][CH2:16]1

Participants

6

Reactant 5

HCID 849Pipecolic AcidHCID 8752,3-Dihydroxybutanedioic AcidHCID 923Sodium ionHCID 961HydroxideHCID 110638611H-Benzo[d]imidazole-2-sulfonyl chloride

Product 1

HCID 230007441-(1H-benzo[d]imidazol-2-ylsulfonyl)-2-piperidinecarboxylic acid

Sources & evidence

ORD record
ord-66fa7fcaf57547c29980eb70932ba354
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…