2-(((3-(Trifluoromethyl)phenyl)methyl)sulfonyl)acetonitrile → 2-(3-Trifluoromethyl-phenylmethanesulfonyl)-4-trifluoromethylsulfanyl-butyronitrile

HRID 80405Notes

Reaction equation

HRID 80405 reaction equation
[F:1][C:2]([F:17])([F:16])[C:3]1[CH:4]=[C:5]([CH2:9][S:10]([CH2:13][C:14]#[N:15])(=[O:12])=[O:11])[CH:6]=[CH:7][CH:8]=1.[F:18][C:19]([S:22][CH2:23][CH2:24]OS(C(F)(F)F)(=O)=O)([F:21])[F:20]>>[F:17][C:2]([F:1])([F:16])[C:3]1[CH:4]=[C:5]([CH2:9][S:10]([CH:13]([CH2:24][CH2:23][S:22][C:19]([F:21])([F:20])[F:18])[C:14]#[N:15])(=[O:12])=[O:11])[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 27824342-(((3-(Trifluoromethyl)phenyl)methyl)sulfonyl)acetonitrileHCID 25242028HCID 25242028, compound

Product 1

HCID 866732702-(3-Trifluoromethyl-phenylmethanesulfonyl)-4-trifluoromethylsulfanyl-butyronitrile

Procedure

Compound II-5 was prepared from (3-trifluoromethyl-phenylmethanesulfonyl)-acetonitrile and trifluoro-methanesulfonic acid 2-trifluoromethylsulfanyl-ethyl ester as described for compound II-1.

Sources & evidence

ORD record
ord-ff159c090ba3454aa06da4364b76fc74
Source dataset
uspto-grants-2014_09
Patent number
US08846569B2

Reaction notes

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