Dimethyl Sulfoxide → trans-N1-(5-chloro-4-(6-(cyclohexylmethylamino)pyridin-2-yl)pyrimidin-2-yl)cyclohexane-1,4-diamine
Reaction equation
[CH3:31][S:32]([CH3:33])=[O:34].[CH:23]1([CH2:29][NH2:30])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]1.[Cl:1][c:2]1[c:3](-[c:16]2[n:17][c:18]([F:22])[cH:19][cH:20][cH:21]2)[n:4][c:5]([NH:8][CH:9]2[CH2:10][CH2:11][CH:12]([NH2:15])[CH2:13][CH2:14]2)[n:6][cH:7]1>>[Cl:1][c:2]1[c:3](-[c:16]2[n:17][c:18]([NH:30][CH2:29][CH:23]3[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]3)[cH:19][cH:20][cH:21]2)[n:4][c:5]([NH:8][CH:9]2[CH2:10][CH2:11][CH:12]([NH2:15])[CH2:13][CH2:14]2)[n:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-fbe55673bfd846e8ae13ca6a3a6a6052
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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