Sodium ion → 1-Cyclohexyl-3-[2,6-dichloro-4-(1-isobutyl-1H-pyrazol-4-yl)-benzyl]-pyrrolidin-2-one

HRID 804240Notes

Reaction equation

HRID 804240 reaction equation
[CH2:30]([CH:31]([CH3:32])[CH3:33])[n:34]1[n:35][cH:36][c:37]([B:39]2[O:40][C:41]([CH3:42])([CH3:43])[C:44]([CH3:45])([CH3:46])[O:47]2)[cH:38]1.[CH2:54]([CH2:55][O:56][CH3:57])[O:58][CH3:59].[F:1][C:2]([F:3])([F:4])[S:5]([O:6][c:7]1[cH:8][c:9]([Cl:27])[c:10]([CH2:14][CH:15]2[C:16](=[O:26])[N:17]([CH:20]3[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]3)[CH2:18][CH2:19]2)[c:11]([Cl:13])[cH:12]1)(=[O:28])=[O:29].[Na+:48].[Na+:49].[O-:50][C:51](=[O:52])[O-:53]>>[c:7]1(-[c:37]2[cH:36][n:35][n:34]([CH2:30][CH:31]([CH3:32])[CH3:33])[cH:38]2)[cH:8][c:9]([Cl:27])[c:10]([CH2:14][CH:15]2[C:16](=[O:26])[N:17]([CH:20]3[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]3)[CH2:18][CH2:19]2)[c:11]([Cl:13])[cH:12]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 80711,2-DimethoxyethaneHCID 19660Carbonate IonHCID 27593921-Isobutyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 592994213,5-Dichloro-4-((1-cyclohexyl-2-oxopyrrolidin-3-yl)methyl)phenyl trifluoromethanesulfonate

Product 1

HCID 592993031-Cyclohexyl-3-[2,6-dichloro-4-(1-isobutyl-1H-pyrazol-4-yl)-benzyl]-pyrrolidin-2-one

Sources & evidence

ORD record
ord-4c0306a89e0d4709a4840f0a90df63e9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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