3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole → 1-{4-[1-(1-pyrrolidinylcarbonyl)cyclopropyl]phenyl}-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole
Reaction equation
[F:18][C:19]([c:20]1[n:21][nH:22][c:23]2[c:28]1[CH2:27][CH2:26][CH2:25][CH2:24]2)([F:29])[F:30].[I:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][CH2:16][CH2:17]3)[CH2:9][CH2:10]2)[cH:6][cH:7]1>>[c:2]1(-[n:22]2[n:21][c:20]([C:19]([F:18])([F:29])[F:30])[c:28]3[c:23]2[CH2:24][CH2:25][CH2:26][CH2:27]3)[cH:3][cH:4][c:5]([C:8]2([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][CH2:16][CH2:17]3)[CH2:9][CH2:10]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-85bd8dc0197141f8a4c56145f9a135b9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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