(4-Methoxy-3-methylphenyl)boronic acid → 4-[5-(4-Methoxy-3-methylphenyl)pyridin-3-yl]-1,4-diazatricyclo[4.3.1.13,8]undecane

HRID 80450Notes

Reaction equation

HRID 80450 reaction equation
Br[C:2]1[CH:3]=[C:4]([N:8]2[CH2:16][CH:15]3[CH2:17][N:11]4[CH2:12][CH:13]([CH2:18][CH:9]2[CH2:10]4)[CH2:14]3)[CH:5]=[N:6][CH:7]=1.[CH3:19][O:20][C:21]1[CH:26]=[CH:25][C:24](B(O)O)=[CH:23][C:22]=1[CH3:30]>>[CH3:19][O:20][C:21]1[CH:26]=[CH:25][C:24]([C:2]2[CH:3]=[C:4]([N:8]3[CH2:16][CH:15]4[CH2:17][N:11]5[CH2:12][CH:13]([CH2:18][CH:9]3[CH2:10]5)[CH2:14]4)[CH:5]=[N:6][CH:7]=2)=[CH:23][C:22]=1[CH3:30]

Participants

3

Reactant 2

HCID 2773487(4-Methoxy-3-methylphenyl)boronic acidHCID 866492494-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane

Product 1

HCID 498697164-[5-(4-Methoxy-3-methylphenyl)pyridin-3-yl]-1,4-diazatricyclo[4.3.1.13,8]undecane

Procedure

The title compound was prepared from the product of Example 65A and 4-methoxy-3-methylphenylboronic acid according to General Method B: LC-MS Method D (ESI+) m/z 350.0 (M+H)+, retention time 1.42 minutes.

Sources & evidence

ORD record
ord-4fdd7017d9b04eff98fb2cf8f87b4716
Source dataset
uspto-grants-2014_09
Patent number
US08846661B2

Reaction notes

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