(4-Methoxyphenyl)boronic acid → 4-[5-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-1,4-diazatricyclo[4.3.1.13,8]undecane

Participants

Reaction Steps

The title compound was prepared from the product of Example 105A and 4-methoxyphenylboronic acid according to General Method C: 1H NMR (500 MHz, CDCl3) δ ppm 7.35 (d, 2 H), 7.28 (s, 1 H), 6.88 (d, 2 H), 4.75-4.71 (m, 1 H), 3.64-3.59 (q, 2 H), 3.48-3.40 (q, 2 H), 3.08-3.05 (m, 4 H), 2.29-2.18 (m, 3 H), 1.88-1.80 (m, 3 H); LC-MS Method D (ESI+) m/z 342.0 (M+H)+, retention time 1.44 minutes.

Provenance & Evidence