3-Fluoro-4-methoxyphenylboronic acid → 8-Chloro-3-(3-fluoro-4-methoxyphenyl)-7-hydroxy-1-naphthonitrile

HRID 804588Notes

Reaction equation

HRID 804588 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:14]#[N:15])[c:5]2[c:6]([Cl:13])[c:7]([OH:12])[cH:8][cH:9][c:10]2[cH:11]1.[F:16][c:17]1[cH:18][c:19]([B:25]([OH:26])[OH:27])[cH:20][cH:21][c:22]1[O:23][CH3:24]>>[c:2]1(-[c:19]2[cH:18][c:17]([F:16])[c:22]([O:23][CH3:24])[cH:21][cH:20]2)[cH:3][c:4]([C:14]#[N:15])[c:5]2[c:6]([Cl:13])[c:7]([OH:12])[cH:8][cH:9][c:10]2[cH:11]1

Participants

3

Reactant 2

HCID 27821943-Fluoro-4-methoxyphenylboronic acidHCID 114829513-Bromo-8-chloro-7-hydroxy-1-naphthonitrile

Product 1

HCID 114728998-Chloro-3-(3-fluoro-4-methoxyphenyl)-7-hydroxy-1-naphthonitrile

Sources & evidence

ORD record
ord-2c337c0a46074c09927d2c0d38c9806f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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