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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 804672Generated: October 27, 2026

Hydrochloric Acid → 4-benzyl-7-((4-(4-chlorophenyl)piperidin-1-yl)methyl)-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one

https://huagongshe.com/reaction/804672

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPropionitrileHCID 7854—
ReactantIodide IonHCID 30165—
ReactantDiisopropylethylamineHCID 81531—
Reactant4-(4-Chlorophenyl)piperidineHCID 1203613—
ReactantCyanomethyl(trimethyl)phosphaniumHCID 10514345—
Reactant4-benzyl-7-(hydroxymethyl)-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-oneHCID 58324463—
Product4-benzyl-7-((4-(4-chlorophenyl)piperidin-1-yl)methyl)-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-oneHCID 46864444—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-fc3a87e9be264480b54dd551605b0983
Source noteTest data from https://doi.org/10.1039/C8SC04228D