Chloroform → 2,5-dihydro-alpha-hydroxy-1-(3-methoxyphenyl)-3-methyl-5-oxo-alpha-trifluoromethyl-1H-pyrazole-4-acetic acid methyl ester

HRID 804820Notes

Reaction equation

HRID 804820 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5](-[n:9]2[nH:10][c:11]([CH3:15])[cH:12][c:13]2=[O:14])[cH:6][cH:7][cH:8]1.[CH:26]([Cl:27])([Cl:28])[Cl:29].[F:16][C:17]([C:18]([C:19](=[O:20])[O:21][CH3:22])=[O:23])([F:24])[F:25]>>[CH3:1][O:2][c:3]1[cH:4][c:5](-[n:9]2[nH:10][c:11]([CH3:15])[c:12]([C:18]([C:17]([F:16])([F:24])[F:25])([C:19](=[O:20])[O:21][CH3:22])[OH:23])[c:13]2=[O:14])[cH:6][cH:7][cH:8]1

Participants

4

Reactant 3

HCID 6212ChloroformHCID 2734931Methyl 3,3,3-trifluoro-2-oxopropanoateHCID 544140731-(3-Methoxyphenyl)-3-methyl-5-pyrazolone

Product 1

HCID 441398202,5-dihydro-alpha-hydroxy-1-(3-methoxyphenyl)-3-methyl-5-oxo-alpha-trifluoromethyl-1H-pyrazole-4-acetic acid methyl ester

Sources & evidence

ORD record
ord-db25143f76384527840d9aba2013ec06
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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