2-Ethylbenzimidazole → 2-[1-[[2-(2-Ethylbenzimidazol-1-yl)-9-methyl-6-(3-methylmorpholin-4-yl)purin-8-yl]methyl]piperidin-4-yl]propan-2-ol

HRID 804892Notes

Reaction equation

[C:41](=[O:42])([O-:43])[O-:44].[CH2:30]([CH3:31])[c:32]1[nH:33][c:34]2[c:35]([n:36]1)[cH:37][cH:38][cH:39][cH:40]2.[Cl:1][c:2]1[n:3][c:4]([N:23]2[CH:24]([CH3:29])[CH2:25][O:26][CH2:27][CH2:28]2)[c:5]2[n:6][c:7]([CH2:12][N:13]3[CH2:14][CH2:15][CH:16]([C:19]([CH3:20])([CH3:21])[OH:22])[CH2:17][CH2:18]3)[n:8]([CH3:11])[c:9]2[n:10]1.[Cs+:45].[Cs+:46].[O:47]1[CH2:48][CH2:49][O:50][CH2:51][CH2:52]1.[O:55]=[C:56]([CH:57]=[CH:58][c:59]1[cH:60][cH:61][cH:62][cH:63][cH:64]1)[CH:65]=[CH:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1.[O:73]=[C:74]([CH:75]=[CH:76][c:77]1[cH:78][cH:79][cH:80][cH:81][cH:82]1)[CH:83]=[CH:84][c:85]1[cH:86][cH:87][cH:88][cH:89][cH:90]1.[O:91]=[C:92]([CH:93]=[CH:94][c:95]1[cH:96][cH:97][cH:98][cH:99][cH:100]1)[CH:101]=[CH:102][c:103]1[cH:104][cH:105][cH:106][cH:107][cH:108]1.[Pd:53].[Pd:54]>>[c:2]1(-[n:33]2[c:32]([CH2:30][CH3:31])[n:36][c:35]3[c:34]2[cH:40][cH:39][cH:38][cH:37]3)[n:3][c:4]([N:23]2[CH:24]([CH3:29])[CH2:25][O:26][CH2:27][CH2:28]2)[c:5]2[n:6][c:7]([CH2:12][N:13]3[CH2:14][CH2:15][CH:16]([C:19]([CH3:20])([CH3:21])[OH:22])[CH2:17][CH2:18]3)[n:8]([CH3:11])[c:9]2[n:10]1