5-bromo-N-(1-hydroxy-2-methylpropan-2-yl)pyridine-3-sulfonamide → 5-[5-(4-Chloro-phenyl)-7-cyclopropyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridine-3-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH:14]4[CH2:15][CH2:16]4)[cH:13]2)[n:17][cH:18][c:19]3[C:20]#[CH:21])[cH:6][cH:7]1.[OH:22][CH2:23][C:24]([CH3:25])([CH3:26])[NH:27][S:28](=[O:29])(=[O:30])[c:31]1[cH:32][n:33][cH:34][c:35]([Br:37])[cH:36]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH:14]4[CH2:15][CH2:16]4)[cH:13]2)[n:17][cH:18][c:19]3[C:20]#[C:21][c:35]2[cH:34][n:33][cH:32][c:31]([S:28]([NH:27][C:24]([CH2:23][OH:22])([CH3:25])[CH3:26])(=[O:29])=[O:30])[cH:36]2)[cH:6][cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-74c9a01942e64b3da1d2084675c32039
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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