Methyl 2-(3-bromo-5-chlorophenyl)acetate → (5-Chloro-2'-{[(4-chloro-benzyloxycarbonyl)-ethyl-amino]-methyl}-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

HRID 804973Notes

Reaction equation

HRID 804973 reaction equation
[CH3:35][O:36][C:37]([CH2:38][c:39]1[cH:40][c:41]([Br:46])[cH:42][c:43]([Cl:45])[cH:44]1)=[O:47].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][O:7][C:8]([N:9]([CH2:10][c:11]2[c:12]([B:21]3[O:22][C:23]([CH3:24])([CH3:25])[C:26]([CH3:27])([CH3:28])[O:29]3)[cH:13][cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)[CH2:30][CH3:31])=[O:32])[cH:33][cH:34]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][O:7][C:8]([N:9]([CH2:10][c:11]2[c:12](-[c:41]3[cH:40][c:39]([CH2:38][C:37]([O:36][CH3:35])=[O:47])[cH:44][c:43]([Cl:45])[cH:42]3)[cH:13][cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)[CH2:30][CH3:31])=[O:32])[cH:33][cH:34]1

Participants

3

Reactant 2

HCID 58149292Methyl 2-(3-bromo-5-chlorophenyl)acetateHCID 66607359Ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-carbamic acid 4-chloro-benzyl ester

Product 1

HCID 66607031(5-Chloro-2'-{[(4-chloro-benzyloxycarbonyl)-ethyl-amino]-methyl}-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

Sources & evidence

ORD record
ord-fb9bbcbd19554e0b801a6e421e8d71eb
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…