HRID805145

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID642811

3-Amino-6-bromopyridine

C5H5BrN2

HCID3697076

8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,4-dioxaspiro[4.5]dec-7-ene

C14H23BO4

HCID68003354

未命名化合物

结构：O=C(CNc1ncnc2ccc(C(F)(F)F)cc12)NC1CNC1

HCID68003594

未命名化合物

PRODUCTS

生成物

结构：Nc1ccc(C2CCC(N3CC(NC(=O)CNc4ncnc5ccc(C(F)(F)F)cc45)C3)CC2)nc1

HCID54772207

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c9b13e457b1c449ba15e2cb894cb1924
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br:15][c:16]1[n:17][cH:18][c:19]([NH2:20])[cH:21][cH:22]1.[CH3:23][C:24]1([CH3:25])[C:26]([CH3:27])([CH3:28])[O:29][B:30]([C:31]2=[CH:40][CH2:39][C:34]3([CH2:33][CH2:32]2)[O:35][CH2:36][CH2:37][O:38]3)[O:41]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]2)[n:6][cH:7]1.[NH:42]1[CH2:43][CH:44]([NH:46][C:47]([CH2:48][NH:49][c:50]2[n:51][cH:52][n:53][c:54]3[cH:55][cH:56][c:57]([C:60]([F:61])([F:62])[F:63])[cH:58][c:59]23)=[O:64])[CH2:45]1>>[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][CH:11]([N:42]3[CH2:43][CH:44]([NH:46][C:47]([CH2:48][NH:49][c:50]4[n:51][cH:52][n:53][c:54]5[cH:55][cH:56][c:57]([C:60]([F:61])([F:62])[F:63])[cH:58][c:59]45)=[O:64])[CH2:45]3)[CH2:12][CH2:13]2)[n:6][cH:7]1