6-Bromopyridin-3-amine → N-(1-(4-(5-aminopyridin-2-yl)cyclohexyl)azetidin-3-yl)-2-((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamide

HRID 805145Notes

Reaction equation

[Br:15][c:16]1[n:17][cH:18][c:19]([NH2:20])[cH:21][cH:22]1.[CH3:23][C:24]1([CH3:25])[C:26]([CH3:27])([CH3:28])[O:29][B:30]([C:31]2=[CH:40][CH2:39][C:34]3([CH2:33][CH2:32]2)[O:35][CH2:36][CH2:37][O:38]3)[O:41]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]2)[n:6][cH:7]1.[NH:42]1[CH2:43][CH:44]([NH:46][C:47]([CH2:48][NH:49][c:50]2[n:51][cH:52][n:53][c:54]3[cH:55][cH:56][c:57]([C:60]([F:61])([F:62])[F:63])[cH:58][c:59]23)=[O:64])[CH2:45]1>>[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][CH:11]([N:42]3[CH2:43][CH:44]([NH:46][C:47]([CH2:48][NH:49][c:50]4[n:51][cH:52][n:53][c:54]5[cH:55][cH:56][c:57]([C:60]([F:61])([F:62])[F:63])[cH:58][c:59]45)=[O:64])[CH2:45]3)[CH2:12][CH2:13]2)[n:6][cH:7]1