2-Amino-5-(3-fluorophenyl)-1,3-thiazole-4-carboxylic acid → N-[[2-[2-amino-5-(3-fluorophenyl)-1,3-thiazole-4-carbonyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-3,5-dimethyl-1,2-oxazole-4-carboxamide

HRID 805265Notes

Reaction equation

HRID 805265 reaction equation
[CH:1]12[NH:2][CH:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]3[c:12]([CH3:17])[n:13][o:14][c:15]3[CH3:16])[CH2:4][CH:5]1[CH2:6]2.[NH2:18][c:19]1[s:20][c:21](-[c:27]2[cH:28][c:29]([F:33])[cH:30][cH:31][cH:32]2)[c:22]([C:24](=[O:25])[OH:26])[n:23]1>>[CH:1]12[N:2]([C:24]([c:22]3[c:21](-[c:27]4[cH:28][c:29]([F:33])[cH:30][cH:31][cH:32]4)[s:20][c:19]([NH2:18])[n:23]3)=[O:25])[CH:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]3[c:12]([CH3:17])[n:13][o:14][c:15]3[CH3:16])[CH2:4][CH:5]1[CH2:6]2

Participants

3

Reactant 2

HCID 574371792-Amino-5-(3-fluorophenyl)-1,3-thiazole-4-carboxylic acidHCID 178434753HCID 178434753, compound

Product 1

HCID 178434754N-[[2-[2-amino-5-(3-fluorophenyl)-1,3-thiazole-4-carbonyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-3,5-dimethyl-1,2-oxazole-4-carboxamide

Sources & evidence

ORD record
ord-6be341d0a32c4f9881d9e1461c66cd59
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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