(1-(2-morpholinoethyl)-1H-pyrazol-4-yl)boronic acid → 1-(2-chloro-3,6-difluorobenzyl)-7-{1-[2-(morpholin-4-yl)ethyl]-1H-pyrazol-4-yl}-1,2,3,4-tetrahydropyrazino[2,3-b]pyrazine

Participants

Reaction Steps

The entitled compound was prepared from 7-bromo-1-(2-chloro-3,6-difluorobenzyl)-1,2,3,4-tetrahydropyrazino[2,3-b]pyrazine and 1-(2-Morpholinoethyl)-1H-pyrazole-4-boronic acid, pinacol ester using Suzuki coupling conditions as described in Example 1.

Provenance & Evidence