3-Oxo-3-(3-pyrimidin-5-yl-phenyl)-propionic acid tert-butyl ester → {4-Chloro-5-isobutylamino-2-[3-oxo-3-(3-pyrimidin-5-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:20])[cH:10][c:11]([Cl:19])[c:12]([NH:14][CH2:15][CH:16]([CH3:17])[CH3:18])[cH:13]1)=[O:21].[C:22]([CH3:24])([CH3:25])([O:26][C:27](=[O:23])[CH2:28][C:29]([c:30]1[cH:31][c:32](-[c:36]2[cH:37][n:38][cH:39][n:40][cH:41]2)[cH:33][cH:34][cH:35]1)=[O:42])[CH3:43]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:20][C:27](=[O:26])[CH2:28][C:29]([c:30]2[cH:31][c:32](-[c:36]3[cH:37][n:38][cH:39][n:40][cH:41]3)[cH:33][cH:34][cH:35]2)=[O:42])[cH:10][c:11]([Cl:19])[c:12]([NH:14][CH2:15][CH:16]([CH3:17])[CH3:18])[cH:13]1)=[O:21]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-bb6250934752412e9ba97f80a0d5766d
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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