HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Diethyl-2-propanamine → Methyl N-{5-bromo-3-[(2-chloro-3,6-difluorobenzyl)amino]pyrazin-2-yl}-beta-alaninate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Diethyl-2-propanamine | HCID 521913 | — |
| Reactant | 2-Chloro-3,6-difluorobenzylamine | HCID 2773545 | — |
| Reactant | methyl N-(3,5-dibromopyrazin-2-yl)-beta-alaninate | HCID 86659428 | — |
| Product | Methyl N-{5-bromo-3-[(2-chloro-3,6-difluorobenzyl)amino]pyrazin-2-yl}-beta-alaninate | HCID 86659427 | — |
Reaction Steps
Methyl N-{5-bromo-3-[(2-chloro-3,6-difluorobenzyl)amino]pyrazin-2-yl}-β-alaninate was prepared from methyl N-(3,5-dibromopyrazin-2-yl)-β-alaninate and 2-chloro-3,6-difluorobenzylamine in the presence of N,N-diethylisopropylamine as described in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846664B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-47cfcfe66c8b487ab840a86e8593c189 |
| Source note | uspto-grants-2014_09 |