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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 805813Generated: October 29, 2026

Water → N-[1-(4-{2-[2-Oxo-4-(thiophen-2-ylmethoxy)-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide

https://huagongshe.com/reaction/805813

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantMethanesulfonyl chlorideHCID 31297—
Reactant4-AcetamidopiperidineHCID 1445156—
Reactant1-[2-(4-Hydroxymethyl-phenyl)-ethyl]-4-(thiophen-2-ylmethoxy)-1H-pyridin-2-oneHCID 67006859—
ProductN-[1-(4-{2-[2-Oxo-4-(thiophen-2-ylmethoxy)-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamideHCID 58042709—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-33a4ab5235a84835b8b84084e15a155e
Source noteTest data from https://doi.org/10.1039/C8SC04228D