反应详情

To the compound 61a obtained in Step (1) (90 mg) was dissolved in acetic acid (2 ml), zinc powder (180 mg) was added, and the mixture was stirred at room temperature for 3 hours. The insolubles were filtered out, then the filtrate was concentrated, and the residue was purified by preparative thin layer chromatography (silica gel, chloroform/methanol/acetic acid=8/1/0.25) to obtain the title compound (17.4 mg).

1. filtrationThe insolubles were filtered out
2. concentrationthe filtrate was concentrated
3. customthe residue was purified by preparative thin layer chromatography (silica gel, chloroform/methanol/acetic acid=8/1/0.25)