2-Acetylphenylboronic acid → 1-(2-(2-((5-ethoxy-2-fluoro-3-isopropoxyphenyl)(4-(5-methyl-1,2,4-oxadiazol-3-yl)phenylamino)methyl)-1-trityl-1H-imidazol-4-yl)phenyl)ethanone
Reaction equation
[Br:1][c:2]1[n:3][c:4]([CH:26]([NH:27][c:28]2[cH:29][cH:30][c:31](-[c:34]3[n:35][o:36][c:37]([CH3:39])[n:38]3)[cH:32][cH:33]2)[c:40]2[c:41]([F:53])[c:42]([O:49][CH:50]([CH3:51])[CH3:52])[cH:43][c:44]([O:46][CH2:47][CH3:48])[cH:45]2)[n:5]([C:7]([c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:6]1.[C:54]([CH3:55])(=[O:56])[c:57]1[c:58]([B:63]([OH:64])[OH:65])[cH:59][cH:60][cH:61][cH:62]1>>[c:2]1(-[c:58]2[c:57]([C:54]([CH3:55])=[O:56])[cH:62][cH:61][cH:60][cH:59]2)[n:3][c:4]([CH:26]([NH:27][c:28]2[cH:29][cH:30][c:31](-[c:34]3[n:35][o:36][c:37]([CH3:39])[n:38]3)[cH:32][cH:33]2)[c:40]2[c:41]([F:53])[c:42]([O:49][CH:50]([CH3:51])[CH3:52])[cH:43][c:44]([O:46][CH2:47][CH3:48])[cH:45]2)[n:5]([C:7]([c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:6]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d29648793b004111b0f3e2df3f8ff516
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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