Sodium ion → N-(6-(5-amino-6-chloropyridin-3-yl)imidazo[1,2-b]pyridazin-2-yl)acetamide

HRID 805987Notes

Reaction equation

HRID 805987 reaction equation
[Cl:15][c:16]1[n:17][cH:18][c:19]([CH:23]2[O:24][C:25]([CH3:26])([CH3:27])[C:28]([CH3:29])([CH3:30])[O:31]2)[cH:20][c:21]1[NH2:22].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[n:6]([n:7]1)[cH:8][c:9]([NH:11][C:12]([CH3:13])=[O:14])[n:10]2.[Na+:32].[Na+:33].[O-:34][C:35](=[O:36])[O-:37]>>[c:2]1(-[c:19]2[cH:18][n:17][c:16]([Cl:15])[c:21]([NH2:22])[cH:20]2)[cH:3][cH:4][c:5]2[n:6]([n:7]1)[cH:8][c:9]([NH:11][C:12]([CH3:13])=[O:14])[n:10]2

Participants

5

Reactant 4

HCID 923Sodium ion2×HCID 19660Carbonate IonHCID 59519510N-(6-chloroimidazo[1,2-b]pyridazin-2-yl)acetamideHCID 866319652-Chloro-5-(4,4,5,5-tetramethyl-1,3-dioxolan-2-yl)pyridin-3-amine

Product 1

HCID 57749424N-(6-(5-amino-6-chloropyridin-3-yl)imidazo[1,2-b]pyridazin-2-yl)acetamide

Sources & evidence

ORD record
ord-a295e0e943fd48948423eb0739d5902c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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