反应详情

温度

80 °C

In a pressure tube with one end sealed, add 193 mg 5-bromo-2-chloropyrimidine (1.0 mmol) and 285 mg cyclopropylamine (5.0 mmol) in 3.0 mL ethanol, and the mixture is heated to 80° C. and stirred for 3 h. The reaction mixture was cooled to room temperature, and 203 mg solid product was collected by filtration for direct use yield: 95%).

1. customIn a pressure tube with one end sealed
2. temperatureThe reaction mixture was cooled to room temperature
3. filtration203 mg solid product was collected by filtration for direct use yield: 95%)