[2-Ethyl-8-fluoro-3-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinolin-5-yloxy]acetic acid methyl ester → [4-Difluoromethoxy-2-ethyl-8-fluoro-3-(4-methoxybenzyl)quinolin-5-yloxy]acetic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([CH2:4][O:5][c:6]1[c:7]2[c:8](=[O:28])[c:9]([CH2:19][c:20]3[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]3)[c:10]([CH2:17][CH3:18])[nH:11][c:12]2[c:13]([F:16])[cH:14][cH:15]1)=[O:29].[Cl:30][C:31]([F:32])([F:33])[O:34][C:35](=[O:36])[CH3:37]>>[CH3:1][O:2][C:3]([CH2:4][O:5][c:6]1[c:7]2[c:8]([O:28][CH:31]([F:32])[F:33])[c:9]([CH2:19][c:20]3[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]3)[c:10]([CH2:17][CH3:18])[n:11][c:12]2[c:13]([F:16])[cH:14][cH:15]1)=[O:29]Participants
3
Sources & evidence
- ORD record
- ord-aab2fac5ae894f539820659a20dde3c4
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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