4-Fluorobenzylic alcohol → 2-[(benzyloxycarbonyl)(methyl)amino]-6-chloro-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic Acid 4-fluorobenzyl Ester
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]([n:12]1[c:13](=[O:32])[c:14]2[cH:15][cH:16][c:17]([Cl:31])[cH:18][c:19]2[c:20](-[c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:21]1[C:22](=[O:23])[OH:24])[CH3:33].[F:34][c:35]1[cH:36][cH:37][c:38]([CH2:39][OH:40])[cH:41][cH:42]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]([n:12]1[c:13](=[O:32])[c:14]2[cH:15][cH:16][c:17]([Cl:31])[cH:18][c:19]2[c:20](-[c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:21]1[C:22]([O:23][CH2:39][c:38]1[cH:37][cH:36][c:35]([F:34])[cH:42][cH:41]1)=[O:24])[CH3:33]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-c902bb9937984723930f68fb1fbd0f03
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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