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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 806166Generated: October 29, 2026

Ethylene Glycol → 2-Amino-6-(2-hydroxyethoxy)-N-(5-phenoxy-thiophen-2-ylmethyl)-nicotinamide

https://huagongshe.com/reaction/806166

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylene GlycolHCID 174—
ReactantAmmoniumHCID 223—
ReactantChlorideHCID 312—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantAcetonitrileHCID 6342—
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantHydrideHCID 166653—
Reactant2-aminochloro-N-(5-phenoxy-thiophen-2-ylmethyl)-nicotinamideHCID 23130498—
Product2-Amino-6-(2-hydroxyethoxy)-N-(5-phenoxy-thiophen-2-ylmethyl)-nicotinamideHCID 23130546—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-2463a906919b4157af881b833c9dc44e
Source noteTest data from https://doi.org/10.1039/C8SC04228D